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Anemia Toolkit

Iron Supplementation in Infants: A Reflection on Hepcidin and Fractional Iron Absorption

Publication Date:
Anemia
This editorial discusses the implications of a study that assesses the effect of iron dosing schedules on plasma hepcidin and iron absorption in high-risk infants in Kenya and found that iron absorption administered in a variety of methods in a pediatric population and found that less frequent dosing results in increased fractional absorption of iron (the amount of iron absorbed per dose).
Anemia Toolkit

The Effect of Iron Dosing Schedules on Plasma Hepcidin and Iron Absorption in Kenyan Infants

Publication Date:
Anemia
This study assessed iron uptake in infants in Kenya who received three different regimens of iron supplementations via stable iron isotopes.
Anemia Toolkit

The Inclusion of Folic Acid in Weekly Iron-Folic Acid Supplements Confers no Additional Benefit on Anemia Reduction in Nonpregnant Women: A Randomized Controlled Trial in Malaysia

Publication Date:
Anemia
This paper reports the results of a secondary analysis of a randomized controlled trial in Malaysia that examined whether the inclusion of folic acid in weekly iron and folic acid supplements in nonpregnant women aged 18–45 years conferred any benefit on hemoglobin concentration, anemia reduction, or iron status, over iron alone.
Anemia Toolkit

Age, Ethnicity, Glucose-6-Phosphate Dehydrogenase Deficiency, Micronutrient Powder Intake, and Biomarkers of Micronutrient Status, Infection, and Inflammation are Associated with Anemia Among Children 6–59 Months in Nepal

Publication Date:
Anemia
This study used cross-sectional data from the 2016 Nepal National Micronutrient Status Survey to evaluate factors associated with anemia in a nationally representative, population-based sample of children 6–59 months.
Anemia Toolkit

Reticulocyte Haemoglobin Equivalent (RET-He) as an Early Marker of Responsiveness to Oral Iron Supplementation

Publication Date:
Anemia
This study evaluated the analytical performance of reticulocyte hemoglobin equivalent as an early marker of responsiveness to iron supplementation in Cambodian women aged 18–45 years, who received 60 mg elemental iron for 12 weeks.
Anemia Toolkit

The Effect of Oral Iron Supplementation on Gut Microbial Composition: A Secondary Analysis of a Double-Blind, Randomized Controlled Trial Among Cambodian Women of Reproductive Age

Publication Date:
Anemia
This study is a secondary analysis of a double-blind, randomized controled trial of oral iron supplementation in Cambodian women of reproductive age, which examined the effects of two oral iron supplements of differing bioavailability—ferrous sulfate or ferrous bisglycinate- or placebo on the gut microbiome.
Anemia Toolkit

The Effects of Oral Ferrous Bisglycinate Supplementation on Hemoglobin and Ferritin Concentrations in Adults and Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Publication Date:
Anemia
This systematic review of randomized controled trials evaluates the effects of ferrous bisglycinate supplementation compared with other iron supplements on hemoglobin and ferritin concentrations, and gastrointestinal adverse events, among pregnant women and children.
Anemia Toolkit

Can Automated Hematology Analyzers Predict the Presence of a Genetic Hemoglobinopathy? An Analysis of Hematological Biomarkers in Cambodian Women

Publication Date:
Anemia
This study evaluated the accuracy of a Sysmex XN-1000 hematology analyzer in identifying genetic hemoglobinopathies in nonpregnant Cambodian women and to assess the ability of six complete blood count biomarkers to predict a genetic hemoglobinopathy.
Anemia Toolkit

A School-Based Weekly Iron and Folic Acid Supplementation Program Effectively Reduces Anemia in a Prospective Cohort of Ghanaian Adolescent Girls

Publication Date:
Anemia
This study evaluated the effectiveness of school-based weekly iron and folic acid supplementation program in reducing the burden of anemia and increasing hemoglobin concentrations in two regions of Ghana.
Anemia Toolkit

Predictors of Anaemia Among Adolescent Schoolchildren of Ghana

Publication Date:
Anemia
This study identifies factors associated with hemoglobin concentration and anaemia among school-attending adolescent girls and boys from 115 schools across the various regions of Ghana.
Anemia Toolkit

Barriers to and Facilitators of Iron and Folic Acid Supplementation Within a School-Based Integrated Nutrition and Health Promotion Program Among Ghanaian Adolescent Girls

Publication Date:
Anemia
This study describes the barriers to and facilitators of program fidelity to a school-based anemia reduction program with weekly iron and folic acid supplementation among adolescent girls in Ghana.
Anemia Toolkit

An Integrated Infant and Young Child Feeding and Micronutrient Powder Intervention Does Not Affect Anemia, Iron Status, or Vitamin A Status among Children Aged 12–23 Months in Eastern Uganda

Publication Date:
Anemia
This study evaluated the impact of an integrated infant and young child feeding and micronutrient powder intervention on anemia and micronutrient status among children aged 12–23 months in Eastern Uganda.
Anemia Toolkit

The VitMin Lab Sandwich-ELISA Assays for Iron and Inflammation Markers Compared Well with Clinical Analyzer Reference-Type Assays in Subsamples of the Nepal National Micronutrient Status Survey

Publication Date:
Anemia
This study evaluates the analytical performance of the VitMin Lab enzyme-linked immunosorbent assay (ELISA) assays for serum ferritin, soluble transferrin receptor, C-reactive protein, and α-1-acid glycoprotein in comparison to a Roche clinical analyzer on serum samples from children 6–59 months and nonpregnant women who participated in the 2016 Nepal National Micronutrient Status survey.
Anemia Toolkit

Factors Associated with Anaemia Among Adolescent Boys and Girls 10–19 Years Old in Nepal

Publication Date:
Anemia
This secondary analysis of data from the 2016 Nepal National Micronutrient Status Survey evaluates the factors associated with anemia, derived from altitude- and smoking-adjusted hemoglobin concentration values, among nationally representative samples of adolescents 10–19 years.
Anemia Toolkit

Factors Associated with Anaemia in a Nationally Representative Sample of Nonpregnant Women of Reproductive Age in Nepal

Publication Date:
Anemia
This secondary analysis of cross-sectional data from the 2016 Nepal National Micronutrient Status Survey evaluates the factors associated with anemia, derived from altitude- and smoking-adjusted hemoglobin concentration values, among nationally representative sample of nonpregnant women 15– 49 years.
Anemia Toolkit

Evaluation of Hemoglobin Cutoff Levels to Define Anemia Among Healthy Individuals

Publication Date:
Anemia
This study uses cross-sectional data from 30 household, population-based nutrition surveys of preschool children aged 6 to 59 months and nonpregnant women aged 15 to 49 years across 25 countries to evaluate the current World Health Organization hemoglobin cutoffs for defining anemia among persons who are apparently healthy, and to assess threshold validity with soluble transferrin receptor, whi
Anemia Toolkit

A Qualitative Analysis of Program Fidelity and Perspectives of Educators and Parents after Two Years of the Girls' Iron-Folate Tablet Supplementation (GIFTS) Program in Ghanaian Secondary Schools

Publication Date:
Anemia
To address the burden of anemia in adolescent girls in Ghana, the Girls' Iron-Folate Tablet Supplementation program was established in 2017. This study qualitatively describes the differences in program implementation among schools and across time after two years of implementation, and highlights potential factors that drive such differences.
Anemia Toolkit

Anemia in Bolivian Children: A Comparative Analysis Among Three Regions of Different Altitudes

Publication Date:
Anemia
This paper analyzes four population-based demographic and health surveys conducted in Bolivia between 1998 and 2016 to understand trends in anemia in children from 6 to 59 months of age by selected sociodemographic characteristics and three categories of altitude: low, medium, and high.
Anemia Toolkit

Spatial Variation and Attributable Risk Factors of Anaemia Among Young Children in Uganda: Evidence from a Nationally Representative Survey

Publication Date:
Anemia
This study describes the spatial variation and attributable risk factors of anemia at the national level in Uganda among children aged 6–59 months, using data from the 2016 Uganda Demographic and Health Survey.
Anemia Toolkit

Association between Hemoglobin and Elevation among School-aged Children: A Verification of Proposed Adjustments

Publication Date:
Anemia
Hemoglobin increases with elevation as an adaptive response to lower blood oxygen saturation. This secondary data analysis examines the cross-sectional association between hemoglobin and elevation among school-aged children with data from nine population-based surveys.