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Anemia Toolkit
Integrating and Coordinating Programs for the Management of Anemia Across the Life Course
Publication Date:
Anemia
This narrative review describes the determinants of anemia and outlines opportunities for comprehensive anemia programming, systems strengthening, and implementation research approaches for preschool children, adolescent girls, and pregnant and nonpregnant women of reproductive age
Anemia Toolkit
WHO Guideline on Use of Ferritin Concentrations to Assess Iron Status in Individuals and Populations
Publication Date:
Anemia
This guideline provides global, evidence-informed recommendations on the use of indicators for assessing a population’s iron status and application of the use of ferritin concentrations for monitoring and evaluating iron interventions.
Anemia Toolkit
Accelerating Anaemia Reduction: A Comprehensive Framework for Action
Publication Date:
Anemia
This document is an output of a World Health Organization cross-program initiative aiming to improve the prevention, diagnosis, and management of anaemia and thereby accelerate reduction of its prevalence.
Anemia Toolkit
Comprehensive Framework for Integrated Action on the Prevention, Diagnosis, and Management of Anemia: An Introduction
Publication Date:
Anemia
In 2021, the World Health Organization (WHO) announced in 2021 a commitment to develop a comprehensive framework for integrated action on the prevention, diagnosis, and management of anemia and to establish an Anaemia Action Alliance to support the implementation of the framework.
Anemia Toolkit
The Role of Modelling to Inform Context-Specific Anaemia Programming
Publication Date:
Anemia
Using the example of a microsimulation study to estimate net benefits and cost-effectiveness of micronutrient powder programmes for young children, this paper proposes the use of modeling tools to evaluate benefits, risks, and costs of interventions, often in the absence of comprehensive information about all three.
Anemia Toolkit
Adjusting Iron and Vitamin A Status in Settings of Inflammation: A Sensitivity Analysis of the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) Approach
Publication Date:
Anemia
Accurate assessment of iron and vitamin A status is needed to inform public health decisions, but most population-level iron and vitamin A biomarkers are independently influenced by inflammation.
Anemia Toolkit
The Co-Occurrence of Overweight and Micronutrient Deficiencies or Anemia Among Women of Reproductive Age In Malawi
Publication Date:
Anemia
Using data from nonpregnant women aged 15–49 years in the 2015–2016 Malawi Micronutrient Survey, this paper described the prevalence of double burden pf malnutrition (overweight and obesity, and anemia) among Malawian women
Anemia Toolkit
Use of the Electronic Health Record to Assess Prevalence of Anemia and Iron Deficiency in Pregnancy
Publication Date:
Anemia
This paper explores the use of electronic health records for surveillance of the prevalence of anemia, iron deficiency, and iron-deficiency anemia during first-trimester pregnancies in the United States.
Anemia Toolkit
Baseline Hemoglobin, Hepcidin, Ferritin, and Total Body Iron Stores are Equally Strong Diagnostic Predictors of a Hemoglobin Response to 12 Weeks of Daily Iron Supplementation in Cambodian Women
Publication Date:
Anemia
This paper reports the performance of hematological biomarkers (hemoglobin [Hb], measured with both a hematology analyzer and a HemoCue; inflammation-adjusted ferritin; soluble transferrin receptor; reticulocyte Hb; hepcidin; mean corpuscular volume; inflammation-adjusted total body iron stores; total iron binding capacity; and transferrin saturation) in predicting a hemoglobin response in nonp
Anemia Toolkit
The Inclusion of Folic Acid in Weekly Iron-Folic Acid Supplements Confers no Additional Benefit on Anemia Reduction in Nonpregnant Women: A Randomized Controlled Trial in Malaysia
Publication Date:
Anemia
This paper reports the results of a secondary analysis of a randomized controlled trial in Malaysia that examined whether the inclusion of folic acid in weekly iron and folic acid supplements in nonpregnant women aged 18–45 years conferred any benefit on hemoglobin concentration, anemia reduction, or iron status, over iron alone.
Anemia Toolkit
The Effect of Iron Dosing Schedules on Plasma Hepcidin and Iron Absorption in Kenyan Infants
Publication Date:
Anemia
This study assessed iron uptake in infants in Kenya who received three different regimens of iron supplementations via stable iron isotopes.
Anemia Toolkit
Iron Supplementation in Infants: A Reflection on Hepcidin and Fractional Iron Absorption
Publication Date:
Anemia
This editorial discusses the implications of a study that assesses the effect of iron dosing schedules on plasma hepcidin and iron absorption in high-risk infants in Kenya and found that iron absorption administered in a variety of methods in a pediatric population and found that less frequent dosing results in increased fractional absorption of iron (the amount of iron absorbed per dose).
Anemia Toolkit
Oral Iron Supplementation in Iron-Deficient Women: How Much and How Often?
Publication Date:
Anemia
This review on oral iron supplementation provides an overview of recently conducted stable iron isotope studies conducted in young women to quantify iron absorption.
Anemia Toolkit
Anemia Prevalence and Anthropometric Status of Indigenous Women and Young Children in Rural Botswana: The San People
Publication Date:
Anemia
This study reports the results of a cross-sectional survey to assess the anemia prevalence among and anthropometric indices of women and young children belonging to the San People (also known as the Basarwa or Bushmen), an Indigenous minority group, in Ghanzi District in Botswana.
Anemia Toolkit
Can Automated Hematology Analyzers Predict the Presence of a Genetic Hemoglobinopathy? An Analysis of Hematological Biomarkers in Cambodian Women
Publication Date:
Anemia
This study evaluated the accuracy of a Sysmex XN-1000 hematology analyzer in identifying genetic hemoglobinopathies in nonpregnant Cambodian women and to assess the ability of six complete blood count biomarkers to predict a genetic hemoglobinopathy.
Anemia Toolkit
The Effects of Oral Ferrous Bisglycinate Supplementation on Hemoglobin and Ferritin Concentrations in Adults and Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Publication Date:
Anemia
This systematic review of randomized controled trials evaluates the effects of ferrous bisglycinate supplementation compared with other iron supplements on hemoglobin and ferritin concentrations, and gastrointestinal adverse events, among pregnant women and children.
Anemia Toolkit
The Effect of Oral Iron Supplementation on Gut Microbial Composition: A Secondary Analysis of a Double-Blind, Randomized Controlled Trial Among Cambodian Women of Reproductive Age
Publication Date:
Anemia
This study is a secondary analysis of a double-blind, randomized controled trial of oral iron supplementation in Cambodian women of reproductive age, which examined the effects of two oral iron supplements of differing bioavailability—ferrous sulfate or ferrous bisglycinate- or placebo on the gut microbiome.
Anemia Toolkit
Reticulocyte Haemoglobin Equivalent (RET-He) as an Early Marker of Responsiveness to Oral Iron Supplementation
Publication Date:
Anemia
This study evaluated the analytical performance of reticulocyte hemoglobin equivalent as an early marker of responsiveness to iron supplementation in Cambodian women aged 18–45 years, who received 60 mg elemental iron for 12 weeks.
Anemia Toolkit
Age, Ethnicity, Glucose-6-Phosphate Dehydrogenase Deficiency, Micronutrient Powder Intake, and Biomarkers of Micronutrient Status, Infection, and Inflammation are Associated with Anemia Among Children 6–59 Months in Nepal
Publication Date:
Anemia
This study used cross-sectional data from the 2016 Nepal National Micronutrient Status Survey to evaluate factors associated with anemia in a nationally representative, population-based sample of children 6–59 months.
Anemia Toolkit
An Integrated Infant and Young Child Feeding and Micronutrient Powder Intervention Does Not Affect Anemia, Iron Status, or Vitamin A Status among Children Aged 12–23 Months in Eastern Uganda
Publication Date:
Anemia
This study evaluated the impact of an integrated infant and young child feeding and micronutrient powder intervention on anemia and micronutrient status among children aged 12–23 months in Eastern Uganda.