Interventions for anemia prevention and control should incorporate an understanding of the biology as well as the assessment of the severity, magnitude, and prevalence of anemia in clinical and public health practice. The biological causes of anemia are complex and multifactorial, calling for a multifaceted approach to its assessment and treatment.

Interventions to reduce anemia, however, fall broadly into two main categories:

  1. Approaches that address anemia via clinical and public health interventions anemia (e.g., delayed cord clamping, malaria control, deworming); and
  2. Approaches that address nutrients alone (e.g., dietary diversification, biofortification, food fortification, supplementation with iron and/or other micronutrients).

The two types of approaches can be targeted to specific population groups at different stages of the life course — mothers (during pregnancy, postpartum, and lactation), infants, young children, and adolescents.

When examining potential interventions against anemia, one must consider several factors, including: genetic mutation prevalence, the role of infection/inflammation in the target population on intervention effectiveness, as well as nutrient delivery methods, bioavailability of nutrients in the context, and the safety of interventions. Nutritional interventions must also consider the broader context of sustainability within food systems, with a focus on cultural factors and indigenous conditions, as well as climate change and environmental factors.

We found 70 resource(s)

Wheat Flour Fortification with Iron for Reducing Anaemia and Improving Iron Status in Populations
Systematic Review published by Cochrane Library in
This Cochrane Systematic Review synthesizes the evidence pertaining to the benefits and harms of wheat flour fortification with iron alone or with other vitamins and minerals in relation to anemia, iron status, and health‐related outcomes in populations over 2 years of age. Evidence from 9 studies suggests a very low to moderate certainty…
Review: Climate Change Impacts on Food Security- Focus on Perennial Cropping Systems and Nutritional Value
Literature Review published by Plant Science in
This review synthesizes evidence on the impact of climate change on fruit and vegetable crops, highlights existing knowledge gaps, and offers approaches to address future challenges using an integrative approach including genomics, phenomics, and future climate models.
Combining the Effects of Increased Atmospheric Carbon Dioxide on Protein, Iron, and Zinc Availability and Projected Climate Change on Global Diets: A Modelling Study
Literature Review published by The Lancet Planetary Health in
This modelling study uses the International Model for Policy Analysis of Agricultural Commodities and Trade to project per capita availability of protein, iron, and zinc in 2050. Findings indicate that, although technological change, market responses, and the effects of CO2 fertilisation on yield are projected to increase global availability of…
Climate Change Has Likely Already Affected Global Food Production
Journal Article published by PLOS One in
This article presents linear regression relationships using weather and reported crop data to assess the potential impact of observed climate change on the yields of the top ten global crops – barley, cassava, maize, oil palm, rapeseed, rice, sorghum, soybean, sugarcane and wheat at ~20,000 political units. Results indicate that impacts of climate…
Public Health Deworming Programmes for Soil‐Transmitted Helminths in Children Living in Endemic Areas
Systematic Review published by Cochrane Library in
This systematic review synthesizes the evidence pertaining to the effects of public health programs to regularly treat all children with deworming drugs on child growth, hemoglobin, cognition, school attendance, school performance, physical fitness, and mortality. Evidence from 50 trials in low-to-high-burden settings suggests substantial evidence…
Food Fortification with Multiple Micronutrients: Impact on Health Outcomes in General Population
Systematic Review published by Cochrane Library in
This Cochrane Systematic Review synthesizes the evidence pertaining to the impact of food fortification with multiple micronutrients on health outcomes in the general population, including men, women, and children.
Maternal and Neonatal Outcomes Related to Iron Supplementation or Iron Status: A Summary of Meta-Analyses
Systematic Review published by The Journal of Maternal-Fetal and Neonatal Medicine in
This review was conducted to derive an umbrella summary of meta-analyses performed to evaluate the effects and associations of iron supplementation or iron status on maternal and birth/neonatal outcomes. Evidence from 16 meta-analyses suggests beneficial effects of multiple-micronutrient supplementation on some neonatal outcomes. Furthermore,…
Fortification of Staple Foods with Vitamin A for Vitamin A Deficiency
Systematic Review published by Cochrane Library in
This Cochrane Systematic Review synthesizes the evidence pertaining to the effects of fortifying staple foods with vitamin A in reducing vitamin A deficiency and improving health‐related outcomes in the general population older than 2 years.